Moisture+

Patient Benefits:

• High-level hydration helps protect dry skin from environmental assaults.
• Contains Intercellular Lipids (ILD’s) and natural Maoisturising Factors (NMF’s), the skin’s own moisturising systems.

Need To Know:

• Dry skin is caused by a depletion of IL’s and NMF’s in the epidermis.  Moisture+ works by helping replenish these cellular components, fortifying the skin’s protective barrier.  Dry skin is almost always sensitive skin.  This is because the IL’s and NMF’s protect the skin from irritants.  When the skin is deficient in these components, environmental irritants can more readily penetrate the epidermis and create sensitivity.

Product Usage:

• Moisture+ may be applied liberally at any time of the day.
• A second layer of Moisture+ can be applied around the eye area to reduce dryness and sensitivity.

Vitamin C (L-ascorbic acid):

• Vitamin C occurs naturally in the skin as a result of dietary intake.  As a result of intrinsic and photo ageing, dietary intake does not result in optimal levels of Vitamin C in the skin.  Naturally-present Vitamin C is degraded by UV radiation and reactive oxygen species.
• Studies with cultured fibroblasts indicate a strong increase in collagen synthesis after exposure to ascorbate.  Vitamin C stimulates the production of collagen in the skin, ameliorating structure and firming skin tone.
• L-ascorbic acid is an excellent free radical scavenger, preventing formation of DNA lesions and visible signs of ageing.  In vitro studies show strong cytoprotective qualities for Vitamin C.
• High dose Vitamin C may improve the performance of skin lightening products and procedures.  In vitro studies have shown the ability of ascorbic acid to interfere in the melanin synthesis.

Vitamin A (Retinol)

• Topically delivered retinol is capable of being metabolised into retinaldehyde and retinoic acid (tretinion) according to theoretical models.
• Retinoic acid is also associated with reversal of photo ageing, causing improvement in epidermal thickness, dysplasia, keratoses and collagen production.
• Clinically, retinol seems to elicit these same anti-photo ageing effects.  The mechanism for this is yet known.
• Retinol is effective in fading pigmentation as it accelerates exfoliation of melanised keratinocytes.
• Retinol assists with cellular differentiation and exfoliation by promoting cleavage of commeocytes from the stratum corneum.
• Retinoic acid is demonstrated to be effective in acne therapy due to its ability to normalise cellular shedding inside individual sebaceous follicles.  It is possible that retinol helps to improve acne by this mechanism.

Vitamin E (Tocopherol acetate)

• Tocopherol acetate has been demonstrated to provide protection against UV damage, including erythema and oedema.
• Clinical studies suggest that the combination of vitamin E and C is more effective that either vitamin applied singly in providing phot-protection.  Added vitamin A completes the vitamin antioxidant profile.

Contraindications:

Pregnancy-toxicity of vitamin A dosage in this formulation in pregnancy is unknown.  Use of this product is not recommended during pregnancy.

LINK

More detailed information on Rationale products can be found on the following link: www.rationaleskincare.com